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Selective binding and transport of protocadherin 15 isoforms by stereocilia unconventional myosins i...

Selective binding and transport of protocadherin 15 isoforms by stereocilia unconventional myosins i...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_45ce34e9424e4923bd57114f2fb7782b

Selective binding and transport of protocadherin 15 isoforms by stereocilia unconventional myosins in a heterologous expression system

About this item

Full title

Selective binding and transport of protocadherin 15 isoforms by stereocilia unconventional myosins in a heterologous expression system

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2022-08, Vol.12 (1), p.13764-13764, Article 13764

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

During hair cell development, the mechanoelectrical transduction (MET) apparatus is assembled at the stereocilia tips, where it coexists with the stereocilia actin regulatory machinery. While the myosin-based tipward transport of actin regulatory proteins is well studied, isoform complexity and built-in redundancies in the MET apparatus have limite...

Alternative Titles

Full title

Selective binding and transport of protocadherin 15 isoforms by stereocilia unconventional myosins in a heterologous expression system

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_45ce34e9424e4923bd57114f2fb7782b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_45ce34e9424e4923bd57114f2fb7782b

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-022-17757-0

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