123 P-MUC1C-ALLO1: A fully allogeneic stem cell memory T cell (TSCM) CAR-T therapy with broad potent...
123 P-MUC1C-ALLO1: A fully allogeneic stem cell memory T cell (TSCM) CAR-T therapy with broad potential in solid tumor
About this item
Full title
Author / Creator
Zhang, Yan , Kozlowska, Anna , Fritz, Jacqueline , Zhao, Yingying , Torre, Claudia Palomino La , Cranert, Stacey , Wang, Steven , Codde, Rebecca , Argus, Elvira , Ibitokou, Samad , Richardson, Vanitra , Jain, Sumiti , Richter, Maximilian , Patil, Deepak , Tan, Yening , Tong, Min , Yao, Lu , Ghoddusi, Majid , Ostertag, Eric , Coronella, Julia and Shedlock, Devon
Publisher
London: BMJ Publishing Group Ltd
Journal title
Language
English
Formats
Publication information
Publisher
London: BMJ Publishing Group Ltd
Subjects
More information
Scope and Contents
Contents
BackgroundWhile CAR-T have demonstrated potent activity against hematologic tumors, less success has been seen with solid tumors. Here we report generation of TSCM-enriched allogeneic MUC1-C-specific CAR T cells, P-MUC1C-ALLO1, with potential for a broad range of solid tumors. The proliferative capacity and metabolic profile of TSCM CAR-T are well-...
Alternative Titles
Full title
123 P-MUC1C-ALLO1: A fully allogeneic stem cell memory T cell (TSCM) CAR-T therapy with broad potential in solid tumor
Authors, Artists and Contributors
Author / Creator
Kozlowska, Anna
Fritz, Jacqueline
Zhao, Yingying
Torre, Claudia Palomino La
Cranert, Stacey
Wang, Steven
Codde, Rebecca
Argus, Elvira
Ibitokou, Samad
Richardson, Vanitra
Jain, Sumiti
Richter, Maximilian
Patil, Deepak
Tan, Yening
Tong, Min
Yao, Lu
Ghoddusi, Majid
Ostertag, Eric
Coronella, Julia
Shedlock, Devon
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_45e6535029b74018bc17d63485684a5a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_45e6535029b74018bc17d63485684a5a
Other Identifiers
E-ISSN
2051-1426
DOI
10.1136/jitc-2021-SITC2021.123
