Predictive MGMT status in a homogeneous cohort of IDH wildtype glioblastoma patients
Predictive MGMT status in a homogeneous cohort of IDH wildtype glioblastoma patients
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Methylation of the O(6)-Methylguanine-DNA methyltransferase (MGMT) promoter is predictive for treatment response in glioblastoma patients. However, precise predictive cutoff values to distinguish "MGMT methylated" from "MGMT unmethylated" patients remain highly debated in terms of pyrosequencing (PSQ) analysis. We retrospectively analyzed a clinica...
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Predictive MGMT status in a homogeneous cohort of IDH wildtype glioblastoma patients
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TN_cdi_doaj_primary_oai_doaj_org_article_46257491055d467c96bc511dbfbdcba7
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_46257491055d467c96bc511dbfbdcba7
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ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-019-0745-z
