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A Stealthiness Evaluation of Main Chain Carboxybetaine Polymer Modified into Liposome

A Stealthiness Evaluation of Main Chain Carboxybetaine Polymer Modified into Liposome

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4643eafd97b5426cbcfc0b614064954f

A Stealthiness Evaluation of Main Chain Carboxybetaine Polymer Modified into Liposome

About this item

Full title

A Stealthiness Evaluation of Main Chain Carboxybetaine Polymer Modified into Liposome

Publisher

Switzerland: MDPI AG

Journal title

Pharmaceutics, 2024-09, Vol.16 (10), p.1271

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Background: Acrylamide polymers with zwitterionic carboxybetaine (CB) side groups have attracted attention as stealth polymers that do not induce antibodies when conjugated to proteins. However, they induce antibodies when modified onto liposomes. We hypothesized that antibodies are produced against polymer backbones rather than CB side groups. Obj...

Alternative Titles

Full title

A Stealthiness Evaluation of Main Chain Carboxybetaine Polymer Modified into Liposome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_4643eafd97b5426cbcfc0b614064954f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4643eafd97b5426cbcfc0b614064954f

Other Identifiers

ISSN

1999-4923

E-ISSN

1999-4923

DOI

10.3390/pharmaceutics16101271

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