AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation
AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation
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Author / Creator
Gélinas, Roselle , Mailleux, Florence , Dontaine, Justine , Bultot, Laurent , Demeulder, Bénédicte , Ginion, Audrey , Daskalopoulos, Evangelos P. , Esfahani, Hrag , Dubois-Deruy, Emilie , Lauzier, Benjamin , Gauthier, Chantal , Olson, Aaron K. , Bouchard, Bertrand , Des Rosiers, Christine , Viollet, Benoit , Sakamoto, Kei , Balligand, Jean-Luc , Vanoverschelde, Jean-Louis , Beauloye, Christophe , Horman, Sandrine and Bertrand, Luc
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
AMP-activated protein kinase (AMPK) has been shown to inhibit cardiac hypertrophy. Here, we show that submaximal AMPK activation blocks cardiomyocyte hypertrophy without affecting downstream targets previously suggested to be involved, such as p70 ribosomal S6 protein kinase, calcineurin/nuclear factor of activated T cells (NFAT) and extracellular...
Alternative Titles
Full title
AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation
Authors, Artists and Contributors
Author / Creator
Mailleux, Florence
Dontaine, Justine
Bultot, Laurent
Demeulder, Bénédicte
Ginion, Audrey
Daskalopoulos, Evangelos P.
Esfahani, Hrag
Dubois-Deruy, Emilie
Lauzier, Benjamin
Gauthier, Chantal
Olson, Aaron K.
Bouchard, Bertrand
Des Rosiers, Christine
Viollet, Benoit
Sakamoto, Kei
Balligand, Jean-Luc
Vanoverschelde, Jean-Louis
Beauloye, Christophe
Horman, Sandrine
Bertrand, Luc
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_46a09b637dfb42aab34016e0737a3bb6
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_46a09b637dfb42aab34016e0737a3bb6
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-02795-4
