Loss of Wwox drives metastasis in triple-negative breast cancer by JAK2/STAT3 axis
Loss of Wwox drives metastasis in triple-negative breast cancer by JAK2/STAT3 axis
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Author / Creator
Chang, Renxu , Song, Lele , Xu, Yi , Wu, Yanjun , Dai, Cheng , Wang, Xinyu , Sun, Xia , Hou, Yingyong , Li, Wei , Zhan, Xianbao and Zhan, Lixing
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Loss of WW domain-containing oxidoreductase (Wwox) expression has been observed in breast cancer (BC). However, its regulatory effects are largely unknown, especially in triple-negative breast cancer (TNBC). Herein, gene expression profiling revealed that JAK/STAT3 pathway was one of the most differentially modulated pathways in basal-like BC cells...
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Full title
Loss of Wwox drives metastasis in triple-negative breast cancer by JAK2/STAT3 axis
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_46a1268fb89a419cb3100d7ee1428ee9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_46a1268fb89a419cb3100d7ee1428ee9
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-05852-8
