Analysis of FCGR3A-p.176Val variants in women with recurrent pregnancy loss and the association with...
Analysis of FCGR3A-p.176Val variants in women with recurrent pregnancy loss and the association with CD16a expression and anti-HLA antibody status
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Natural Killer (NK) cells have been implicated in recurrent pregnancy loss (RPL). The p.Val176Phe (or Val158Phe) Single Nucleotide Polymorphism (SNP) in the
FCGR3A
gene encoding the FcγRIIIA or CD16a receptor has been associated with an enhanced affinity for IgG and stronger NK-mediated antibody-dependent cellular cytotoxicity. We hypothesize...
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Analysis of FCGR3A-p.176Val variants in women with recurrent pregnancy loss and the association with CD16a expression and anti-HLA antibody status
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TN_cdi_doaj_primary_oai_doaj_org_article_46efa02860574504b8b3000d88c02274
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_46efa02860574504b8b3000d88c02274
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-023-32156-9
