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Pharmacokinetics and metabolomics investigation of an orally modified formula of standardized Centel...

Pharmacokinetics and metabolomics investigation of an orally modified formula of standardized Centel...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_46f92f94d82946d1baf9471d1a54b3ca

Pharmacokinetics and metabolomics investigation of an orally modified formula of standardized Centella asiatica extract in healthy volunteers

About this item

Full title

Pharmacokinetics and metabolomics investigation of an orally modified formula of standardized Centella asiatica extract in healthy volunteers

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2021-03, Vol.11 (1), p.6850-13, Article 6850

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The formula of a standardized extract of
Centella asiatica
(ECa 233) was modified to improve its dissolution, with implications for pharmacokinetics and metabolomic profile. This study aimed to understand the resultant changes in disposition kinetics of ECa 233 and alterations to human metabolome after oral administration. This study was a tw...

Alternative Titles

Full title

Pharmacokinetics and metabolomics investigation of an orally modified formula of standardized Centella asiatica extract in healthy volunteers

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_46f92f94d82946d1baf9471d1a54b3ca

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_46f92f94d82946d1baf9471d1a54b3ca

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-021-86267-2

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