Leptin signalling altered in infantile nephropathic cystinosis‐related bone disorder
Leptin signalling altered in infantile nephropathic cystinosis‐related bone disorder
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Publisher
Germany: John Wiley & Sons, Inc
Journal title
Language
English
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Publisher
Germany: John Wiley & Sons, Inc
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Background
The CTNS gene mutation causes infantile nephropathic cystinosis (INC). Patients with INC develop Fanconi syndrome and chronic kidney disease (CKD) with significant bone deformations. C57BL/6 Ctns−/− mice are an animal model for studying INC. Hyperleptinaemia results from the kidney's inability to eliminate the hormone leptin in CKD. C...
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Full title
Leptin signalling altered in infantile nephropathic cystinosis‐related bone disorder
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TN_cdi_doaj_primary_oai_doaj_org_article_470ca496ffff448aaf9ae1af8b63cec7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_470ca496ffff448aaf9ae1af8b63cec7
Other Identifiers
ISSN
2190-5991,2190-6009
E-ISSN
2190-6009
DOI
10.1002/jcsm.13579
