Macrophages directly kill bladder cancer cells through TNF signaling as an early response to BCG the...
Macrophages directly kill bladder cancer cells through TNF signaling as an early response to BCG therapy
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Author / Creator
Publisher
England: The Company of Biologists Ltd
Journal title
Language
English
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Publisher
England: The Company of Biologists Ltd
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Scope and Contents
Contents
The Bacillus Calmette-Guérin (BCG) vaccine is the oldest cancer immunotherapeutic agent in use. Despite its effectiveness, its initial mechanisms of action remain largely unknown. Here, we elucidate the earliest cellular mechanisms involved in BCG-induced tumor clearance. We developed a fast preclinical in vivo assay to visualize in real time and a...
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Full title
Macrophages directly kill bladder cancer cells through TNF signaling as an early response to BCG therapy
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_4716c5b9f9b7457db0f78ab4e953a158
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4716c5b9f9b7457db0f78ab4e953a158
Other Identifiers
ISSN
1754-8403,1754-8411
E-ISSN
1754-8411
DOI
10.1242/dmm.050693
