Intracellular signalling pathways and cytoskeletal functions converge on the psoriasis candidate gen...
Intracellular signalling pathways and cytoskeletal functions converge on the psoriasis candidate gene CCHCR1 expressed at P-bodies and centrosomes
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Publisher
England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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CCHCR1 (Coiled-Coil α-Helical Rod protein 1) is a putative psoriasis candidate gene with the risk alleles CCHCR1*WWCC and *Iso3, the latter inhibiting the translation of isoform 1. CCHCR1 was recently shown to be a centrosomal protein, as well as a component of cytoplasmic processing bodies (P-bodies) that regulate mRNA turnover. The function of CC...
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Full title
Intracellular signalling pathways and cytoskeletal functions converge on the psoriasis candidate gene CCHCR1 expressed at P-bodies and centrosomes
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TN_cdi_doaj_primary_oai_doaj_org_article_4738f60bbc634fd9bf49693a449cf2e9
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4738f60bbc634fd9bf49693a449cf2e9
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ISSN
1471-2164
E-ISSN
1471-2164
DOI
10.1186/s12864-018-4810-y
