Exploring TNFR1: from discovery to targeted therapy development
Exploring TNFR1: from discovery to targeted therapy development
About this item
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Author / Creator
Li, Yingying , Ye, Ruiwei , Dai, Haorui , Lin, Jiayi , Cheng, Yue , Zhou, Yonghong and Lu, Yiming
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
This review seeks to elucidate the therapeutic potential of tumor necrosis factor receptor 1 (TNFR1) and enhance our comprehension of its role in disease mechanisms. As a critical cell-surface receptor, TNFR1 regulates key signaling pathways, such as nuclear factor kappa-B (NF-κB) and mitogen-activated protein kinase (MAPK), which are associated wi...
Alternative Titles
Full title
Exploring TNFR1: from discovery to targeted therapy development
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_476ce202950c486e9f6d76c3d67fcd75
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_476ce202950c486e9f6d76c3d67fcd75
Other Identifiers
ISSN
1479-5876
E-ISSN
1479-5876
DOI
10.1186/s12967-025-06122-0