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Exploring TNFR1: from discovery to targeted therapy development

Exploring TNFR1: from discovery to targeted therapy development

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_476ce202950c486e9f6d76c3d67fcd75

Exploring TNFR1: from discovery to targeted therapy development

About this item

Full title

Exploring TNFR1: from discovery to targeted therapy development

Publisher

England: BioMed Central Ltd

Journal title

Journal of translational medicine, 2025-01, Vol.23 (1), p.71-22, Article 71

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

This review seeks to elucidate the therapeutic potential of tumor necrosis factor receptor 1 (TNFR1) and enhance our comprehension of its role in disease mechanisms. As a critical cell-surface receptor, TNFR1 regulates key signaling pathways, such as nuclear factor kappa-B (NF-κB) and mitogen-activated protein kinase (MAPK), which are associated wi...

Alternative Titles

Full title

Exploring TNFR1: from discovery to targeted therapy development

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_476ce202950c486e9f6d76c3d67fcd75

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_476ce202950c486e9f6d76c3d67fcd75

Other Identifiers

ISSN

1479-5876

E-ISSN

1479-5876

DOI

10.1186/s12967-025-06122-0

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