Downregulation of the endogenous opioid peptides in the dorsal striatum of human alcoholics
Downregulation of the endogenous opioid peptides in the dorsal striatum of human alcoholics
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Switzerland: Frontiers Research Foundation
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Language
English
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Switzerland: Frontiers Research Foundation
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The endogenous opioid peptides dynorphins and enkephalins may be involved in brain-area specific synaptic adaptations relevant for different stages of an addiction cycle. We compared the levels of prodynorphin (PDYN) and proenkephalin (PENK) mRNAs (by qRT-PCR), and dynorphins and enkephalins (by radioimmunoassay) in the caudate nucleus and putamen...
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Full title
Downregulation of the endogenous opioid peptides in the dorsal striatum of human alcoholics
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TN_cdi_doaj_primary_oai_doaj_org_article_47cbe2a4b61a4275911d81212b7e02e0
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_47cbe2a4b61a4275911d81212b7e02e0
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ISSN
1662-5102
E-ISSN
1662-5102
DOI
10.3389/fncel.2015.00187
