A Method for Using Cell-Penetrating Peptides for Loading Plasmid DNA into Secreted Extracellular Ves...
A Method for Using Cell-Penetrating Peptides for Loading Plasmid DNA into Secreted Extracellular Vesicles
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Scope and Contents
Contents
The low bioavailability and high toxicity of plasmid DNA (pDNA)-based therapeutics pose challenges for their in vivo application. Extracellular vesicles (EVs) have great potential to overcome these limitations, as they are biocompatible native cargo carriers. Various methods for loading pDNA into EVs, including electroporation, sonication, and co-i...
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Full title
A Method for Using Cell-Penetrating Peptides for Loading Plasmid DNA into Secreted Extracellular Vesicles
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TN_cdi_doaj_primary_oai_doaj_org_article_47f4e8ca2d934d4f8af3f6f2f2b9d69c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_47f4e8ca2d934d4f8af3f6f2f2b9d69c
Other Identifiers
ISSN
2218-273X
E-ISSN
2218-273X
DOI
10.3390/biom13121751
