Modulation of Ricin Intoxication by the Autophagy Inhibitor EACC
Modulation of Ricin Intoxication by the Autophagy Inhibitor EACC
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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The compound EACC (ethyl (2-(5-nitrothiophene-2-carboxamido) thiophene-3-carbonyl) carbamate) was recently reported to inhibit fusion of autophagosomes with lysosomes in a reversible manner by inhibiting recruitment of syntaxin 17 to autophagosomes. We report here that this compound also provides a strong protection against the protein toxin ricin...
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Full title
Modulation of Ricin Intoxication by the Autophagy Inhibitor EACC
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TN_cdi_doaj_primary_oai_doaj_org_article_48422bd5b74d41ba93fb1a2648f4f9f6
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_48422bd5b74d41ba93fb1a2648f4f9f6
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ISSN
2072-6651
E-ISSN
2072-6651
DOI
10.3390/toxins14050360
