Intranasal Administration of KYCCSRK Peptide Rescues Brain Insulin Signaling Activation and Reduces...
Intranasal Administration of KYCCSRK Peptide Rescues Brain Insulin Signaling Activation and Reduces Alzheimer’s Disease-like Neuropathology in a Mouse Model for Down Syndrome
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Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Down syndrome (DS) is the most frequent genetic cause of intellectual disability and is strongly associated with Alzheimer’s disease (AD). Brain insulin resistance greatly contributes to AD development in the general population and previous studies from our group showed an early accumulation of insulin resistance markers in DS brain, already in chi...
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Full title
Intranasal Administration of KYCCSRK Peptide Rescues Brain Insulin Signaling Activation and Reduces Alzheimer’s Disease-like Neuropathology in a Mouse Model for Down Syndrome
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TN_cdi_doaj_primary_oai_doaj_org_article_484868323ddd4d378354b1b98c3302bb
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_484868323ddd4d378354b1b98c3302bb
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ISSN
2076-3921
E-ISSN
2076-3921
DOI
10.3390/antiox12010111
