Spatiotemporal dynamics of clonal selection and diversification in normal endometrial epithelium
Spatiotemporal dynamics of clonal selection and diversification in normal endometrial epithelium
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Author / Creator
Yamaguchi, Manako , Nakaoka, Hirofumi , Suda, Kazuaki , Yoshihara, Kosuke , Ishiguro, Tatsuya , Yachida, Nozomi , Saito, Kyota , Ueda, Haruka , Sugino, Kentaro , Mori, Yutaro , Yamawaki, Kaoru , Tamura, Ryo , Revathidevi, Sundaramoorthy , Motoyama, Teiichi , Tainaka, Kazuki , Verhaak, Roel G. W. , Inoue, Ituro and Enomoto, Takayuki
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
It has become evident that somatic mutations in cancer-associated genes accumulate in the normal endometrium, but spatiotemporal understanding of the evolution and expansion of mutant clones is limited. To elucidate the timing and mechanism of the clonal expansion of somatic mutations in cancer-associated genes in the normal endometrium, we sequenc...
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Full title
Spatiotemporal dynamics of clonal selection and diversification in normal endometrial epithelium
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TN_cdi_doaj_primary_oai_doaj_org_article_489f82bf348f4647b67f1068544d1ba2
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_489f82bf348f4647b67f1068544d1ba2
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-28568-2
