Mint3 depletion-mediated glycolytic and oxidative alterations promote pyroptosis and prevent the spr...
Mint3 depletion-mediated glycolytic and oxidative alterations promote pyroptosis and prevent the spread of Listeria monocytogenes infection in macrophages
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Listeria monocytogenes
(LM) infection induces pyroptosis, a form of regulated necrosis, in host macrophages via inflammasome activation. Here, we examined the role of Mint3 in macrophages, which promotes glycolysis via hypoxia-inducible factor-1 activation, during the initiation of pyroptosis following LM infection. Our results showed that Mint3...
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Mint3 depletion-mediated glycolytic and oxidative alterations promote pyroptosis and prevent the spread of Listeria monocytogenes infection in macrophages
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TN_cdi_doaj_primary_oai_doaj_org_article_48e7bbad21db40b99c5e3f463f3f8cac
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_48e7bbad21db40b99c5e3f463f3f8cac
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2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-021-03691-y
