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Shiga Toxins: An Update on Host Factors and Biomedical Applications

Shiga Toxins: An Update on Host Factors and Biomedical Applications

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_48ec792fc8d047a2908d637e7d9872ab

Shiga Toxins: An Update on Host Factors and Biomedical Applications

About this item

Full title

Shiga Toxins: An Update on Host Factors and Biomedical Applications

Publisher

Switzerland: MDPI

Journal title

Toxins, 2021-03, Vol.13 (3), p.222

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI

More information

Scope and Contents

Contents

Shiga toxins (Stxs) are classic bacterial toxins and major virulence factors of toxigenic Shigella dysenteriae and enterohemorrhagic Escherichia coli (EHEC). These toxins recognize a glycosphingolipid globotriaosylceramide (Gb3/CD77) as their receptor and inhibit protein synthesis in cells by cleaving 28S ribosomal RNA. They are the major cause of...

Alternative Titles

Full title

Shiga Toxins: An Update on Host Factors and Biomedical Applications

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_48ec792fc8d047a2908d637e7d9872ab

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_48ec792fc8d047a2908d637e7d9872ab

Other Identifiers

ISSN

2072-6651

E-ISSN

2072-6651

DOI

10.3390/toxins13030222

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