Shiga Toxins: An Update on Host Factors and Biomedical Applications
Shiga Toxins: An Update on Host Factors and Biomedical Applications
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Author / Creator
Liu, Yang , Tian, Songhai , Thaker, Hatim and Dong, Min
Publisher
Switzerland: MDPI
Journal title
Language
English
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Publication information
Publisher
Switzerland: MDPI
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Scope and Contents
Contents
Shiga toxins (Stxs) are classic bacterial toxins and major virulence factors of toxigenic Shigella dysenteriae and enterohemorrhagic Escherichia coli (EHEC). These toxins recognize a glycosphingolipid globotriaosylceramide (Gb3/CD77) as their receptor and inhibit protein synthesis in cells by cleaving 28S ribosomal RNA. They are the major cause of...
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Full title
Shiga Toxins: An Update on Host Factors and Biomedical Applications
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Author / Creator
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TN_cdi_doaj_primary_oai_doaj_org_article_48ec792fc8d047a2908d637e7d9872ab
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_48ec792fc8d047a2908d637e7d9872ab
Other Identifiers
ISSN
2072-6651
E-ISSN
2072-6651
DOI
10.3390/toxins13030222