Cryo-EM structure of human O-GlcNAcylation enzyme pair OGT-OGA complex
Cryo-EM structure of human O-GlcNAcylation enzyme pair OGT-OGA complex
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Author / Creator
Lu, Ping , Liu, Yusong , He, Maozhou , Cao, Ting , Yang, Mengquan , Qi, Shutao , Yu, Hongtao and Gao, Haishan
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
O-GlcNAcylation is a conserved post-translational modification that attaches N-acetyl glucosamine (GlcNAc) to myriad cellular proteins. In response to nutritional and hormonal signals, O-GlcNAcylation regulates diverse cellular processes by modulating the stability, structure, and function of target proteins. Dysregulation of O-GlcNAcylation has be...
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Full title
Cryo-EM structure of human O-GlcNAcylation enzyme pair OGT-OGA complex
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TN_cdi_doaj_primary_oai_doaj_org_article_491b1c93a42d4675ba8561d1486b2a0d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_491b1c93a42d4675ba8561d1486b2a0d
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-42427-8
