Tanshinone IIA suppresses the progression of lung adenocarcinoma through regulating CCNA2-CDK2 compl...
Tanshinone IIA suppresses the progression of lung adenocarcinoma through regulating CCNA2-CDK2 complex and AURKA/PLK1 pathway
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Author / Creator
Li, Ziheng , Zhang, Ying , Zhou, Yuan , Wang, Fuqian , Yin, Chao , Ding, Li and Zhang, Shunbo
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Lung adenocarcinoma (LUAD) belongs to a subgroup of non-small cell lung cancer (NSCLC) with an increasing incidence all over the world. Tanshinone IIA (TSA), an active compound of Salvia miltiorrhiza Bunge., has been found to have anti-tumor effects on many tumors, but its anti-LUAD effect and its mechanism have not been reported yet. In this study...
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Full title
Tanshinone IIA suppresses the progression of lung adenocarcinoma through regulating CCNA2-CDK2 complex and AURKA/PLK1 pathway
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TN_cdi_doaj_primary_oai_doaj_org_article_496c6c3dc2a645c2b64d851d115c90dd
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_496c6c3dc2a645c2b64d851d115c90dd
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-03166-2