[ 18 F]F-DED PET imaging of reactive astrogliosis in neurodegenerative diseases: preclinical proof o...
[ 18 F]F-DED PET imaging of reactive astrogliosis in neurodegenerative diseases: preclinical proof of concept and first-in-human data
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Author / Creator
Ballweg, Anna , Klaus, Carolin , Vogler, Letizia , Katzdobler, Sabrina , Wind, Karin , Zatcepin, Artem , Ziegler, Sibylle I , Secgin, Birkan , Eckenweber, Florian , Bohr, Bernd , Bernhardt, Alexander , Fietzek, Urban , Rauchmann, Boris-Stephan , Stoecklein, Sophia , Quach, Stefanie , Beyer, Leonie , Scheifele, Maximilian , Simmet, Marcel , Joseph, Emanuel , Lindner, Simon , Berg, Isabella , Koglin, Norman , Mueller, Andre , Stephens, Andrew W , Bartenstein, Peter , Tonn, Joerg C , Albert, Nathalie L , Kümpfel, Tania , Kerschensteiner, Martin , Perneczky, Robert , Levin, Johannes , Paeger, Lars , Herms, Jochen and Brendel, Matthias
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
Reactive gliosis is a common pathological hallmark of CNS pathology resulting from neurodegeneration and neuroinflammation. In this study we investigate the capability of a novel monoamine oxidase B (MAO-B) PET ligand to monitor reactive astrogliosis in a transgenic mouse model of Alzheimer`s disease (AD). Furthermore, we performed a pilot study in...
Alternative Titles
Full title
[ 18 F]F-DED PET imaging of reactive astrogliosis in neurodegenerative diseases: preclinical proof of concept and first-in-human data
Authors, Artists and Contributors
Author / Creator
Klaus, Carolin
Vogler, Letizia
Katzdobler, Sabrina
Wind, Karin
Zatcepin, Artem
Ziegler, Sibylle I
Secgin, Birkan
Eckenweber, Florian
Bohr, Bernd
Bernhardt, Alexander
Fietzek, Urban
Rauchmann, Boris-Stephan
Stoecklein, Sophia
Quach, Stefanie
Beyer, Leonie
Scheifele, Maximilian
Simmet, Marcel
Joseph, Emanuel
Lindner, Simon
Berg, Isabella
Koglin, Norman
Mueller, Andre
Stephens, Andrew W
Bartenstein, Peter
Tonn, Joerg C
Albert, Nathalie L
Kümpfel, Tania
Kerschensteiner, Martin
Perneczky, Robert
Levin, Johannes
Paeger, Lars
Herms, Jochen
Brendel, Matthias
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_497126e6fe484a14b58f292c7979ad26
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_497126e6fe484a14b58f292c7979ad26
Other Identifiers
ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/s12974-023-02749-2
