1516 Advancing immunotherapy through patient-identified regulators of T cell stemness
1516 Advancing immunotherapy through patient-identified regulators of T cell stemness
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London: BMJ Publishing Group Ltd
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English
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London: BMJ Publishing Group Ltd
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BackgroundEpigenetic reinforcement of T cell exhaustion is a well-established barrier limiting multiple modalities of T cell-based immunotherapies for cancer. Disruption of the epigenetic regulators DNMT3A and TET2 has been previously used to preserve the proliferative capacity of chronically stimulated CD8 T cells in the setting of both chimeric a...
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1516 Advancing immunotherapy through patient-identified regulators of T cell stemness
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TN_cdi_doaj_primary_oai_doaj_org_article_4995e67c99c042a9b064301f1f83e019
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4995e67c99c042a9b064301f1f83e019
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E-ISSN
2051-1426
DOI
10.1136/jitc-2023-SITC2023.1516
