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Correction of β-thalassemia mutant by base editor in human embryos

Correction of β-thalassemia mutant by base editor in human embryos

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_49c70fc4e396433c8efd55708633d7ca

Correction of β-thalassemia mutant by base editor in human embryos

About this item

Full title

Correction of β-thalassemia mutant by base editor in human embryos

Publisher

Beijing: Higher Education Press

Journal title

Protein & cell, 2017-11, Vol.8 (11), p.811-822

Language

English

Formats

Publication information

Publisher

Beijing: Higher Education Press

More information

Scope and Contents

Contents

β-Thalassemia is a global health issue, caused by mutations in the HBB gene. Among these mutations, HBB -28 (A〉G) mutations is one of the three most common mutations in China and Southeast Asia patients with β-thalassemia. Correcting this mutation in human embryos may prevent the disease being passed onto future generations and cure anemia. Here we...

Alternative Titles

Full title

Correction of β-thalassemia mutant by base editor in human embryos

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_49c70fc4e396433c8efd55708633d7ca

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_49c70fc4e396433c8efd55708633d7ca

Other Identifiers

ISSN

1674-800X

E-ISSN

1674-8018

DOI

10.1007/s13238-017-0475-6

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