Central dogma rates and the trade-off between precision and economy in gene expression
Central dogma rates and the trade-off between precision and economy in gene expression
About this item
Full title
Author / Creator
Hausser, Jean , Mayo, Avi , Keren, Leeat and Alon, Uri
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Steady-state protein abundance is set by four rates: transcription, translation, mRNA decay and protein decay. A given protein abundance can be obtained from infinitely many combinations of these rates. This raises the question of whether the natural rates for each gene result from historical accidents, or are there rules that give certain combinat...
Alternative Titles
Full title
Central dogma rates and the trade-off between precision and economy in gene expression
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Author / Creator
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TN_cdi_doaj_primary_oai_doaj_org_article_49c76385217d4abdbed2391068e344b2
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_49c76385217d4abdbed2391068e344b2
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-07391-8
