The lncRNA Neat1 promotes activation of inflammasomes in macrophages
The lncRNA Neat1 promotes activation of inflammasomes in macrophages
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The inflammasome has an essential function in innate immune, responding to a wide variety of stimuli. Here we show that the lncRNA
Neat1
promotes the activation of several inflammasomes.
Neat1
associates with the NLRP3, NLRC4, and AIM2 inflammasomes in mouse macrophages to enhance their assembly and subsequent pro-caspase-1 processing.<...
Alternative Titles
Full title
The lncRNA Neat1 promotes activation of inflammasomes in macrophages
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TN_cdi_doaj_primary_oai_doaj_org_article_49d1bba3ed8642708ffe6e7d44b7822d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_49d1bba3ed8642708ffe6e7d44b7822d
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-09482-6
