Platelet-derived exosomes regulate endothelial cell inflammation and M1 macrophage polarization in c...
Platelet-derived exosomes regulate endothelial cell inflammation and M1 macrophage polarization in coronary artery thrombosis via modulating miR-34a-5p expression
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Author / Creator
Wei, Kangkang , Yu, Lintong , Li, Jinming , Gao, Jie , Chen, Li , Liu, Min , Zhao, Xiaohan , Li, Min , Shi, Dazhuo and Ma, Xiaojuan
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
As the important factors in coronary artery thrombosis, endothelial injury and M1 macrophage polarization are closely related to the expression of miR-34a-5p. Exosomes in plasma are mainly derived from platelets and play an important role in thrombosis. Based on these facts, this study was conducted to investigate the acting mechanism of platelet-d...
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Full title
Platelet-derived exosomes regulate endothelial cell inflammation and M1 macrophage polarization in coronary artery thrombosis via modulating miR-34a-5p expression
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TN_cdi_doaj_primary_oai_doaj_org_article_49d63e26276244b282fa7e5ee44d6a87
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_49d63e26276244b282fa7e5ee44d6a87
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-024-67654-x