Dissecting molecular mechanisms underlying H2O2-induced apoptosis of mouse bone marrow mesenchymal s...
Dissecting molecular mechanisms underlying H2O2-induced apoptosis of mouse bone marrow mesenchymal stem cell: role of Mst1 inhibition
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London: BioMed Central Ltd
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English
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London: BioMed Central Ltd
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Background Bone marrow mesenchymal stem cell (BM-MSC) has been shown to treat pulmonary arterial hypertension (PAH). However, excessive reactive oxygen species (ROS) increases the apoptosis of BM-MSCs, leading to poor survival and engraft efficiency. Thus, improving the ability of BM-MSCs to scavenge ROS may considerably enhance the effectiveness o...
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Dissecting molecular mechanisms underlying H2O2-induced apoptosis of mouse bone marrow mesenchymal stem cell: role of Mst1 inhibition
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TN_cdi_doaj_primary_oai_doaj_org_article_49edcdcaf59e431399ec2f295d526213
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_49edcdcaf59e431399ec2f295d526213
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ISSN
1757-6512
E-ISSN
1757-6512
DOI
10.1186/s13287-020-02041-7
