High‐content screening of drug combinations of an mPGES‐1 inhibitor in multicellular tumor spheroids...
High‐content screening of drug combinations of an mPGES‐1 inhibitor in multicellular tumor spheroids leads to mechanistic insights into neuroblastoma chemoresistance
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United States: John Wiley & Sons, Inc
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English
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United States: John Wiley & Sons, Inc
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High‐throughput drug screening enables the discovery of new anticancer drugs. Although monolayer cell cultures are commonly used for screening, their limited complexity and translational efficiency require alternative models. Three‐dimensional cell cultures, such as multicellular tumor spheroids (MCTS), mimic tumor architecture and offer promising...
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High‐content screening of drug combinations of an mPGES‐1 inhibitor in multicellular tumor spheroids leads to mechanistic insights into neuroblastoma chemoresistance
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TN_cdi_doaj_primary_oai_doaj_org_article_4a29d39e06f844be8b5afb223e6cda70
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4a29d39e06f844be8b5afb223e6cda70
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ISSN
1574-7891
E-ISSN
1878-0261
DOI
10.1002/1878-0261.13502
