Neuronal mitochondria-targeted therapy for Alzheimer's disease by systemic delivery of resveratrol u...
Neuronal mitochondria-targeted therapy for Alzheimer's disease by systemic delivery of resveratrol using dual-modified novel biomimetic nanosystems
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Author / Creator
Han, Yang , Chu, Xiaoyang , Cui, Lin , Fu, Shiyao , Gao, Chunsheng , Li, Yi and Sun, Baoshan
Publisher
England: Taylor & Francis
Journal title
Language
English
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Publication information
Publisher
England: Taylor & Francis
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Scope and Contents
Contents
Reactive oxygen species (ROS)-induced neuronal mitochondrial dysfunction is a key pathologic factor in sporadic Alzheimer's disease (AD). Neuronal mitochondria have been proposed to be a promising therapeutic target for AD, especially for the failures of phase III clinical trials on conventional amyloid-β (Aβ) targeted therapy. However, the efficie...
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Full title
Neuronal mitochondria-targeted therapy for Alzheimer's disease by systemic delivery of resveratrol using dual-modified novel biomimetic nanosystems
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Author / Creator
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_4a2d18a82f03431f9d65fc7076009093
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4a2d18a82f03431f9d65fc7076009093
Other Identifiers
ISSN
1071-7544
E-ISSN
1521-0464
DOI
10.1080/10717544.2020.1745328