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Neuronal mitochondria-targeted therapy for Alzheimer's disease by systemic delivery of resveratrol u...

Neuronal mitochondria-targeted therapy for Alzheimer's disease by systemic delivery of resveratrol u...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4a2d18a82f03431f9d65fc7076009093

Neuronal mitochondria-targeted therapy for Alzheimer's disease by systemic delivery of resveratrol using dual-modified novel biomimetic nanosystems

About this item

Full title

Neuronal mitochondria-targeted therapy for Alzheimer's disease by systemic delivery of resveratrol using dual-modified novel biomimetic nanosystems

Publisher

England: Taylor & Francis

Journal title

Drug delivery, 2020-01, Vol.27 (1), p.502-518

Language

English

Formats

Publication information

Publisher

England: Taylor & Francis

More information

Scope and Contents

Contents

Reactive oxygen species (ROS)-induced neuronal mitochondrial dysfunction is a key pathologic factor in sporadic Alzheimer's disease (AD). Neuronal mitochondria have been proposed to be a promising therapeutic target for AD, especially for the failures of phase III clinical trials on conventional amyloid-β (Aβ) targeted therapy. However, the efficie...

Alternative Titles

Full title

Neuronal mitochondria-targeted therapy for Alzheimer's disease by systemic delivery of resveratrol using dual-modified novel biomimetic nanosystems

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_4a2d18a82f03431f9d65fc7076009093

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4a2d18a82f03431f9d65fc7076009093

Other Identifiers

ISSN

1071-7544

E-ISSN

1521-0464

DOI

10.1080/10717544.2020.1745328

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