Phylogenetic and biochemical analysis of calsequestrin structure and association of its variants wit...
Phylogenetic and biochemical analysis of calsequestrin structure and association of its variants with cardiac disorders
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Calsequestrin is among the most abundant proteins in muscle sarcoplasmic reticulum and displays a high capacity but a low affinity for Ca
2+
binding. In mammals, calsequestrin is encoded by two genes,
CASQ1
and
CASQ2
, which are expressed almost exclusively in skeletal and cardiac muscles, respectively. Phylogenetic analysis indic...
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Full title
Phylogenetic and biochemical analysis of calsequestrin structure and association of its variants with cardiac disorders
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TN_cdi_doaj_primary_oai_doaj_org_article_4a43cc1d4b6b4f6483b48400d4880e09
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4a43cc1d4b6b4f6483b48400d4880e09
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-75097-3
