Targeted delivery of MerTK protein via cell membrane engineered nanoparticle enhances efferocytosis...
Targeted delivery of MerTK protein via cell membrane engineered nanoparticle enhances efferocytosis and attenuates atherosclerosis in diabetic ApoE -/- Mice
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Author / Creator
Qiu, Shuo , Liu, Jiahan , Chen, Jianmei , Li, Yangni , Bu, Te , Li, Zhelong , Zhang, Liang , Sun, Wenqi , Zhou, Tian , Hu, Wei , Yang, Guodong , Yuan, Lijun , Duan, Yunyou and Xing, Changyang
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Clearance of apoptotic cells by efferocytosis is crucial for prevention of atherosclerosis progress, and impaired efferocytosis contributes to the aggravated atherosclerosis.
In this study, we found that diabetic ApoE
mice showed aggravated atherosclerosis as hyperglycemia damaged the efferocytosis capacity at least partially due to decreased...
Alternative Titles
Full title
Targeted delivery of MerTK protein via cell membrane engineered nanoparticle enhances efferocytosis and attenuates atherosclerosis in diabetic ApoE -/- Mice
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_4a52087893c346fcb5991d44fa0d1c4b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4a52087893c346fcb5991d44fa0d1c4b
Other Identifiers
ISSN
1477-3155
E-ISSN
1477-3155
DOI
10.1186/s12951-024-02463-y