KK-LC-1 as a therapeutic target to eliminate ALDH+ stem cells in triple negative breast cancer
KK-LC-1 as a therapeutic target to eliminate ALDH+ stem cells in triple negative breast cancer
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Author / Creator
Bu, Jiawen , Zhang, Yixiao , Wu, Sijin , Li, Haonan , Sun, Lisha , Liu, Yang , Zhu, Xudong , Qiao, Xinbo , Ma, Qingtian , Liu, Chao , Niu, Nan , Xue, Jinqi , Chen, Guanglei , Yang, Yongliang and Liu, Caigang
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Failure to achieve complete elimination of triple negative breast cancer (TNBC) stem cells after adjuvant therapy is associated with poor outcomes. Aldehyde dehydrogenase 1 (ALDH1) is a marker of breast cancer stem cells (BCSCs), and its enzymatic activity regulates tumor stemness. Identifying upstream targets to control ALDH
+
cells may faci...
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Full title
KK-LC-1 as a therapeutic target to eliminate ALDH+ stem cells in triple negative breast cancer
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_4a6a3bc37dc04129b0d0a57674aa4a99
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4a6a3bc37dc04129b0d0a57674aa4a99
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-38097-1
