Daidzein alleviates skin fibrosis by suppressing TGF-β1 signaling pathway via targeting PKM2
Daidzein alleviates skin fibrosis by suppressing TGF-β1 signaling pathway via targeting PKM2
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Author / Creator
Guo, Xiaowei , Li, Wenqi , Ma, Wei , Liu, Yuming , Liu, Zhigang , Jiao, Ran , Yang, Zhongyi , Zhang, Tiantian , Wu, Hongliang , Ai, Xiaoyu , Gu, Xiaoting , Wang, Wendi , Zhou, Honggang , Li, Xiaohe and Yang, Cheng
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Skin fibrosis including keloids, which are characterized including excessive deposition, abnormal proliferation, aggressiveness, and migration of the extracellular matrix of dermal fibroblasts. TGF-β signaling is a classical pro-fibrotic pathway, and it plays a crucial part in the occurrence and progression of skin fibrosis. Daidzein (Dai), an isof...
Alternative Titles
Full title
Daidzein alleviates skin fibrosis by suppressing TGF-β1 signaling pathway via targeting PKM2
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_4a70d580ff0c417186db145d1ed1e5cf
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4a70d580ff0c417186db145d1ed1e5cf
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-025-93007-3
