Androgen-regulated transcription of ESRP2 drives alternative splicing patterns in prostate cancer
Androgen-regulated transcription of ESRP2 drives alternative splicing patterns in prostate cancer
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Author / Creator
Munkley, Jennifer , Li, Ling , Krishnan, S R Gokul , Hysenaj, Gerald , Scott, Emma , Dalgliesh, Caroline , Oo, Htoo Zarni , Maia, Teresa Mendes , Cheung, Kathleen , Ehrmann, Ingrid , Livermore, Karen E , Zielinska, Hanna , Thompson, Oliver , Knight, Bridget , McCullagh, Paul , McGrath, John , Crundwell, Malcolm , Harries, Lorna W , Daugaard, Mads , Cockell, Simon , Barbosa-Morais, Nuno L , Oltean, Sebastian and Elliott, David J
Publisher
England: eLife Sciences Publications Ltd
Journal title
Language
English
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Publisher
England: eLife Sciences Publications Ltd
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Scope and Contents
Contents
Prostate is the most frequent cancer in men. Prostate cancer progression is driven by androgen steroid hormones, and delayed by androgen deprivation therapy (ADT). Androgens control transcription by stimulating androgen receptor (AR) activity, yet also control pre-mRNA splicing through less clear mechanisms. Here we find androgens regulate splicing...
Alternative Titles
Full title
Androgen-regulated transcription of ESRP2 drives alternative splicing patterns in prostate cancer
Authors, Artists and Contributors
Author / Creator
Li, Ling
Krishnan, S R Gokul
Hysenaj, Gerald
Scott, Emma
Dalgliesh, Caroline
Oo, Htoo Zarni
Maia, Teresa Mendes
Cheung, Kathleen
Ehrmann, Ingrid
Livermore, Karen E
Zielinska, Hanna
Thompson, Oliver
Knight, Bridget
McCullagh, Paul
McGrath, John
Crundwell, Malcolm
Harries, Lorna W
Daugaard, Mads
Cockell, Simon
Barbosa-Morais, Nuno L
Oltean, Sebastian
Elliott, David J
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_4a90da626b1545618d58b1a38a177512
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4a90da626b1545618d58b1a38a177512
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.47678