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Androgen-regulated transcription of ESRP2 drives alternative splicing patterns in prostate cancer

Androgen-regulated transcription of ESRP2 drives alternative splicing patterns in prostate cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4a90da626b1545618d58b1a38a177512

Androgen-regulated transcription of ESRP2 drives alternative splicing patterns in prostate cancer

About this item

Full title

Androgen-regulated transcription of ESRP2 drives alternative splicing patterns in prostate cancer

Publisher

England: eLife Sciences Publications Ltd

Journal title

eLife, 2019-09, Vol.8

Language

English

Formats

Publication information

Publisher

England: eLife Sciences Publications Ltd

More information

Scope and Contents

Contents

Prostate is the most frequent cancer in men. Prostate cancer progression is driven by androgen steroid hormones, and delayed by androgen deprivation therapy (ADT). Androgens control transcription by stimulating androgen receptor (AR) activity, yet also control pre-mRNA splicing through less clear mechanisms. Here we find androgens regulate splicing...

Alternative Titles

Full title

Androgen-regulated transcription of ESRP2 drives alternative splicing patterns in prostate cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_4a90da626b1545618d58b1a38a177512

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4a90da626b1545618d58b1a38a177512

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.47678

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