Contemporary HIV-1 consensus Env with AI-assisted redesigned hypervariable loops promote antibody bi...
Contemporary HIV-1 consensus Env with AI-assisted redesigned hypervariable loops promote antibody binding
About this item
Full title
Author / Creator
Bai, Hongjun , Lewitus, Eric , Li, Yifan , Thomas, Paul V. , Zemil, Michelle , Merbah, Mélanie , Peterson, Caroline E. , Thuraisamy, Thujitha , Rees, Phyllis A. , Hajduczki, Agnes , Dussupt, Vincent , Slike, Bonnie , Mendez-Rivera, Letzibeth , Schmid, Annika , Kavusak, Erin , Rao, Mekhala , Smith, Gabriel , Frey, Jessica , Sims, Alicea , Wieczorek, Lindsay , Polonis, Victoria , Krebs, Shelly J. , Ake, Julie A. , Vasan, Sandhya , Bolton, Diane L. , Joyce, M. Gordon , Townsley, Samantha and Rolland, Morgane
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
An effective HIV-1 vaccine must elicit broadly neutralizing antibodies (bnAbs) against highly diverse Envelope glycoproteins (Env). Since Env with the longest hypervariable (HV) loops is more resistant to the cognate bnAbs than Env with shorter HV loops, we redesigned hypervariable loops for updated Env consensus sequences of subtypes B and C and C...
Alternative Titles
Full title
Contemporary HIV-1 consensus Env with AI-assisted redesigned hypervariable loops promote antibody binding
Authors, Artists and Contributors
Author / Creator
Lewitus, Eric
Li, Yifan
Thomas, Paul V.
Zemil, Michelle
Merbah, Mélanie
Peterson, Caroline E.
Thuraisamy, Thujitha
Rees, Phyllis A.
Hajduczki, Agnes
Dussupt, Vincent
Slike, Bonnie
Mendez-Rivera, Letzibeth
Schmid, Annika
Kavusak, Erin
Rao, Mekhala
Smith, Gabriel
Frey, Jessica
Sims, Alicea
Wieczorek, Lindsay
Polonis, Victoria
Krebs, Shelly J.
Ake, Julie A.
Vasan, Sandhya
Bolton, Diane L.
Joyce, M. Gordon
Townsley, Samantha
Rolland, Morgane
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_4aed98c53021448ba001318c61974fb7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4aed98c53021448ba001318c61974fb7
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-48139-x
