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Senescent cells inhibit mouse myoblast differentiation via the SASP-lipid 15d-PGJ2 mediated modifica...

Senescent cells inhibit mouse myoblast differentiation via the SASP-lipid 15d-PGJ2 mediated modifica...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4b26cba46b57456e9cf1be5ddfbddafb

Senescent cells inhibit mouse myoblast differentiation via the SASP-lipid 15d-PGJ2 mediated modification and control of HRas

About this item

Full title

Senescent cells inhibit mouse myoblast differentiation via the SASP-lipid 15d-PGJ2 mediated modification and control of HRas

Publisher

Cambridge: eLife Sciences Publications Ltd

Journal title

eLife, 2024-08, Vol.13

Language

English

Formats

Publication information

Publisher

Cambridge: eLife Sciences Publications Ltd

More information

Scope and Contents

Contents

Senescent cells are characterized by multiple features such as increased expression of senescence-associated β-galactosidase activity (SA β-gal) and cell cycle inhibitors such as p21 or p16. They accumulate with tissue damage and dysregulate tissue homeostasis. In the context of skeletal muscle, it is known that agents used for chemotherapy such as...

Alternative Titles

Full title

Senescent cells inhibit mouse myoblast differentiation via the SASP-lipid 15d-PGJ2 mediated modification and control of HRas

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_4b26cba46b57456e9cf1be5ddfbddafb

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4b26cba46b57456e9cf1be5ddfbddafb

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.95229

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