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Breast cancer chemotherapy induces vascular dysfunction and hypertension through NOX4 dependent mech...

Breast cancer chemotherapy induces vascular dysfunction and hypertension through NOX4 dependent mech...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4b3b8954d7104657a53492a95dc463f4

Breast cancer chemotherapy induces vascular dysfunction and hypertension through NOX4 dependent mechanism

About this item

Full title

Breast cancer chemotherapy induces vascular dysfunction and hypertension through NOX4 dependent mechanism

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2022-07, Vol.132 (13)

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Cardiovascular disease is the major cause of morbidity and mortality in breast cancer survivors. Chemotherapy contributes to this risk. We aimed to define the mechanisms of long-term vascular dysfunction caused by neoadjuvant chemotherapy (NACT) and identify novel therapeutic targets.We studied arteries from postmenopausal women who had undergone b...

Alternative Titles

Full title

Breast cancer chemotherapy induces vascular dysfunction and hypertension through NOX4 dependent mechanism

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_4b3b8954d7104657a53492a95dc463f4

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4b3b8954d7104657a53492a95dc463f4

Other Identifiers

ISSN

1558-8238,0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI149117

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