The starvation hormone, fibroblast growth factor-21, extends lifespan in mice
The starvation hormone, fibroblast growth factor-21, extends lifespan in mice
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England: eLife Sciences Publications Ltd
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English
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England: eLife Sciences Publications Ltd
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Fibroblast growth factor-21 (FGF21) is a hormone secreted by the liver during fasting that elicits diverse aspects of the adaptive starvation response. Among its effects, FGF21 induces hepatic fatty acid oxidation and ketogenesis, increases insulin sensitivity, blocks somatic growth and causes bone loss. Here we show that transgenic overexpression...
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The starvation hormone, fibroblast growth factor-21, extends lifespan in mice
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TN_cdi_doaj_primary_oai_doaj_org_article_4b4ce4845cdd40c5b506669b2962b9ef
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4b4ce4845cdd40c5b506669b2962b9ef
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.00065
