Routine sub-2.5 Å cryo-EM structure determination of GPCRs
Routine sub-2.5 Å cryo-EM structure determination of GPCRs
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Cryo-electron microscopy (cryo-EM) of small membrane proteins, such as G protein-coupled receptors (GPCRs), remains challenging. Pushing the performance boundaries of the technique requires quantitative knowledge about the contribution of multiple factors. Here, we present an in-depth analysis and optimization of the main experimental parameters in...
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Routine sub-2.5 Å cryo-EM structure determination of GPCRs
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TN_cdi_doaj_primary_oai_doaj_org_article_4b98c85f04bd463f9b6c1fcd192b0ef8
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4b98c85f04bd463f9b6c1fcd192b0ef8
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-24650-3
