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Microfluidic device with brain extracellular matrix promotes structural and functional maturation of...

Microfluidic device with brain extracellular matrix promotes structural and functional maturation of...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4baaa6ea520348a5bdc13ee2f2a1412c

Microfluidic device with brain extracellular matrix promotes structural and functional maturation of human brain organoids

About this item

Full title

Microfluidic device with brain extracellular matrix promotes structural and functional maturation of human brain organoids

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2021-08, Vol.12 (1), p.4730-4730, Article 4730

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Brain organoids derived from human pluripotent stem cells provide a highly valuable in vitro model to recapitulate human brain development and neurological diseases. However, the current systems for brain organoid culture require further improvement for the reliable production of high-quality organoids. Here, we demonstrate two engineering elements...

Alternative Titles

Full title

Microfluidic device with brain extracellular matrix promotes structural and functional maturation of human brain organoids

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_4baaa6ea520348a5bdc13ee2f2a1412c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4baaa6ea520348a5bdc13ee2f2a1412c

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-021-24775-5

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