Log in to save to my catalogue

Morphological screening of mesenchymal mammary tumor organoids to identify drugs that reverse epithe...

Morphological screening of mesenchymal mammary tumor organoids to identify drugs that reverse epithe...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4bf1f86424d4458c89d66da69cca86c8

Morphological screening of mesenchymal mammary tumor organoids to identify drugs that reverse epithelial-mesenchymal transition

About this item

Full title

Morphological screening of mesenchymal mammary tumor organoids to identify drugs that reverse epithelial-mesenchymal transition

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2021-07, Vol.12 (1), p.4262-13, Article 4262

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The epithelial-mesenchymal transition (EMT) has been implicated in conferring stem cell properties and therapeutic resistance to cancer cells. Therefore, identification of drugs that can reprogram EMT may provide new therapeutic strategies. Here, we report that cells derived from claudin-low mammary tumors, a mesenchymal subtype of triple-negative...

Alternative Titles

Full title

Morphological screening of mesenchymal mammary tumor organoids to identify drugs that reverse epithelial-mesenchymal transition

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_4bf1f86424d4458c89d66da69cca86c8

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4bf1f86424d4458c89d66da69cca86c8

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-021-24545-3

How to access this item