Novel protein complexes containing autophagy and UPS components regulate proteasome-dependent PARK2...
Novel protein complexes containing autophagy and UPS components regulate proteasome-dependent PARK2 recruitment onto mitochondria and PARK2-PARK6 activity during mitophagy
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Autophagy is an evolutionarily conserved eukaryotic cellular mechanism through which cytosolic fragments, misfolded/aggregated proteins and organelles are degraded and recycled. Priming of mitochondria through ubiquitylation is required for the clearance the organelle by autophagy (mitophagy). Familial Parkinson’s Disease-related proteins, includin...
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Novel protein complexes containing autophagy and UPS components regulate proteasome-dependent PARK2 recruitment onto mitochondria and PARK2-PARK6 activity during mitophagy
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TN_cdi_doaj_primary_oai_doaj_org_article_4c0b871a164c40d997c2cd1c55e069a3
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4c0b871a164c40d997c2cd1c55e069a3
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-022-05339-x
