Divergent mutational processes distinguish hypoxic and normoxic tumours
Divergent mutational processes distinguish hypoxic and normoxic tumours
About this item
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Author / Creator
PCAWG Consortium , Övriga starka forskningsmiljöer , Faculty of Medicine , Medicinska fakulteten , Other Strong Research Environments , LUCC: Lund University Cancer Centre , Forskningsgrupp Lungcancer , Bröstcancer-genetik , Institutionen för kliniska vetenskaper, Lund , Section I , Lunds universitet , Familjär bröstcancer , Research Group Lung Cancer , Sektion I , Department of Clinical Sciences, Lund , Familial Breast Cancer , Bröst/lungcancer , Profilområden och andra starka forskningsmiljöer , Lund University , Profile areas and other strong research environments , Breastcancer-genetics , LUCC: Lunds universitets cancercentrum , Breast/lungcancer , Bhandari, Vinayak , Li, Constance H. , Bristow, Robert G. and Boutros, Paul C.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Many primary tumours have low levels of molecular oxygen (hypoxia), and hypoxic tumours respond poorly to therapy. Pan-cancer molecular hallmarks of tumour hypoxia remain poorly understood, with limited comprehension of its associations with specific mutational processes, non-coding driver genes and evolutionary features. Here, as part of the ICGC/...
Alternative Titles
Full title
Divergent mutational processes distinguish hypoxic and normoxic tumours
Authors, Artists and Contributors
Author / Creator
Övriga starka forskningsmiljöer
Faculty of Medicine
Medicinska fakulteten
Other Strong Research Environments
LUCC: Lund University Cancer Centre
Forskningsgrupp Lungcancer
Bröstcancer-genetik
Institutionen för kliniska vetenskaper, Lund
Section I
Lunds universitet
Familjär bröstcancer
Research Group Lung Cancer
Sektion I
Department of Clinical Sciences, Lund
Familial Breast Cancer
Bröst/lungcancer
Profilområden och andra starka forskningsmiljöer
Lund University
Profile areas and other strong research environments
Breastcancer-genetics
LUCC: Lunds universitets cancercentrum
Breast/lungcancer
Bhandari, Vinayak
Li, Constance H.
Bristow, Robert G.
Boutros, Paul C.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_4c1bcf031d81481c82255bf73212374c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4c1bcf031d81481c82255bf73212374c
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-14052-x
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