Sericin promotes chondrogenic proliferation and differentiation via glycolysis and Smad2/3 TGF-β sig...
Sericin promotes chondrogenic proliferation and differentiation via glycolysis and Smad2/3 TGF-β signaling inductions and alleviates inflammation in three-dimensional models
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Knee osteoarthritis is a chronic joint disease mainly characterized by cartilage degeneration. The treatment is challenging due to the lack of blood vessels and nerve supplies in cartilaginous tissue, causing a prominent limitation of regenerative capacity. Hence, we investigated the cellular promotional and anti-inflammatory effects of sericin,
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Sericin promotes chondrogenic proliferation and differentiation via glycolysis and Smad2/3 TGF-β signaling inductions and alleviates inflammation in three-dimensional models
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TN_cdi_doaj_primary_oai_doaj_org_article_4c37b2f1319843faab4cf2be95b129c2
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4c37b2f1319843faab4cf2be95b129c2
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2045-2322
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2045-2322
DOI
10.1038/s41598-024-62516-y