Evaluation of the Spider (Phlogiellus genus) Phlotoxin 1 and Synthetic Variants as Antinociceptive D...
Evaluation of the Spider (Phlogiellus genus) Phlotoxin 1 and Synthetic Variants as Antinociceptive Drug Candidates
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Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Over the two last decades, venom toxins have been explored as alternatives to opioids to treat chronic debilitating pain. At present, approximately 20 potential analgesic toxins, mainly from spider venoms, are known to inhibit with high affinity the NaV1.7 subtype of voltage-gated sodium (NaV) channels, the most promising genetically validated anti...
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Evaluation of the Spider (Phlogiellus genus) Phlotoxin 1 and Synthetic Variants as Antinociceptive Drug Candidates
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TN_cdi_doaj_primary_oai_doaj_org_article_4c3c1d6c69fd4589bfd424c05935a392
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4c3c1d6c69fd4589bfd424c05935a392
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ISSN
2072-6651
E-ISSN
2072-6651
DOI
10.3390/toxins11090484
