Selective activation of STAT3 and STAT5 dictates the fate of myeloid progenitor cells
Selective activation of STAT3 and STAT5 dictates the fate of myeloid progenitor cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The molecular programs that govern the directed differentiation of myeloid progenitor cells are still poorly defined. Using a previously established immortalized, phenotypically normal myeloid progenitor cell model mEB8-ER, we unveil a new mechanism mediated by STAT5 and STAT3 at a bifurcation point of myeloid progenitor cell-fate specification. We...
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Selective activation of STAT3 and STAT5 dictates the fate of myeloid progenitor cells
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TN_cdi_doaj_primary_oai_doaj_org_article_4c49f55633c5433bbe8ddb84bd7e9456
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4c49f55633c5433bbe8ddb84bd7e9456
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ISSN
2058-7716
E-ISSN
2058-7716
DOI
10.1038/s41420-023-01575-y