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Selective activation of STAT3 and STAT5 dictates the fate of myeloid progenitor cells

Selective activation of STAT3 and STAT5 dictates the fate of myeloid progenitor cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4c49f55633c5433bbe8ddb84bd7e9456

Selective activation of STAT3 and STAT5 dictates the fate of myeloid progenitor cells

About this item

Full title

Selective activation of STAT3 and STAT5 dictates the fate of myeloid progenitor cells

Publisher

London: Nature Publishing Group UK

Journal title

Cell death discovery, 2023-07, Vol.9 (1), p.274-274, Article 274

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The molecular programs that govern the directed differentiation of myeloid progenitor cells are still poorly defined. Using a previously established immortalized, phenotypically normal myeloid progenitor cell model mEB8-ER, we unveil a new mechanism mediated by STAT5 and STAT3 at a bifurcation point of myeloid progenitor cell-fate specification. We...

Alternative Titles

Full title

Selective activation of STAT3 and STAT5 dictates the fate of myeloid progenitor cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_4c49f55633c5433bbe8ddb84bd7e9456

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4c49f55633c5433bbe8ddb84bd7e9456

Other Identifiers

ISSN

2058-7716

E-ISSN

2058-7716

DOI

10.1038/s41420-023-01575-y

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