Downregulation of fibulin‐4 inhibits autophagy and promotes the sensitivity of esophageal squamous c...
Downregulation of fibulin‐4 inhibits autophagy and promotes the sensitivity of esophageal squamous cell carcinoma cells to apatinib by activating the Akt‐mTOR signaling pathway
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Full title
Author / Creator
Chen, Xiangyu , Wang, Jianyu , Song, Liang , Yu, Yang , Shi, Mo , Jiang, Wenpeng , Liu, Xiangyan and He, Xiaopeng
Publisher
Melbourne: John Wiley & Sons Australia, Ltd
Journal title
Language
English
Formats
Publication information
Publisher
Melbourne: John Wiley & Sons Australia, Ltd
Subjects
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Scope and Contents
Contents
Background
Fibulin‐4, namely, EFEMP2, is an essential matricellular protein associated with a variety of malignancies. The aim of this study was to explore the role of fibulin‐4 in the progression of esophageal squamous cell carcinoma (ESCC), as well as its effect on ESCC sensitivity to apatinib treatment.
Methods
The expression of fibulin...
Alternative Titles
Full title
Downregulation of fibulin‐4 inhibits autophagy and promotes the sensitivity of esophageal squamous cell carcinoma cells to apatinib by activating the Akt‐mTOR signaling pathway
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_4c5a344a8b114065b00f76385214b620
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4c5a344a8b114065b00f76385214b620
Other Identifiers
ISSN
1759-7706
E-ISSN
1759-7714
DOI
10.1111/1759-7714.14595