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Downregulation of fibulin‐4 inhibits autophagy and promotes the sensitivity of esophageal squamous c...

Downregulation of fibulin‐4 inhibits autophagy and promotes the sensitivity of esophageal squamous c...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4c5a344a8b114065b00f76385214b620

Downregulation of fibulin‐4 inhibits autophagy and promotes the sensitivity of esophageal squamous cell carcinoma cells to apatinib by activating the Akt‐mTOR signaling pathway

About this item

Full title

Downregulation of fibulin‐4 inhibits autophagy and promotes the sensitivity of esophageal squamous cell carcinoma cells to apatinib by activating the Akt‐mTOR signaling pathway

Publisher

Melbourne: John Wiley & Sons Australia, Ltd

Journal title

Thoracic cancer, 2022-09, Vol.13 (18), p.2592-2605

Language

English

Formats

Publication information

Publisher

Melbourne: John Wiley & Sons Australia, Ltd

More information

Scope and Contents

Contents

Background
Fibulin‐4, namely, EFEMP2, is an essential matricellular protein associated with a variety of malignancies. The aim of this study was to explore the role of fibulin‐4 in the progression of esophageal squamous cell carcinoma (ESCC), as well as its effect on ESCC sensitivity to apatinib treatment.
Methods
The expression of fibulin...

Alternative Titles

Full title

Downregulation of fibulin‐4 inhibits autophagy and promotes the sensitivity of esophageal squamous cell carcinoma cells to apatinib by activating the Akt‐mTOR signaling pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_4c5a344a8b114065b00f76385214b620

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4c5a344a8b114065b00f76385214b620

Other Identifiers

ISSN

1759-7706

E-ISSN

1759-7714

DOI

10.1111/1759-7714.14595

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