Comprehensive molecular characterization of lung tumors implicates AKT and MYC signaling in adenocar...
Comprehensive molecular characterization of lung tumors implicates AKT and MYC signaling in adenocarcinoma to squamous cell transdifferentiation
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Author / Creator
Quintanal-Villalonga, Alvaro , Taniguchi, Hirokazu , Zhan, Yingqian A. , Hasan, Maysun M. , Chavan, Shweta S. , Meng, Fanli , Uddin, Fathema , Allaj, Viola , Manoj, Parvathy , Shah, Nisargbhai S. , Chan, Joseph M. , Ciampricotti, Metamia , Chow, Andrew , Offin, Michael , Ray-Kirton, Jordana , Egger, Jacklynn D. , Bhanot, Umesh K. , Linkov, Irina , Asher, Marina , Roehrl, Michael H. , Ventura, Katia , Qiu, Juan , de Stanchina, Elisa , Chang, Jason C. , Rekhtman, Natasha , Houck-Loomis, Brian , Koche, Richard P. , Yu, Helena A. , Sen, Triparna and Rudin, Charles M.
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
Lineage plasticity, the ability to transdifferentiate among distinct phenotypic identities, facilitates therapeutic resistance in cancer. In lung adenocarcinomas (LUADs), this phenomenon includes small cell and squamous cell (LUSC) histologic transformation in the context of acquired resistance to targeted inhibition of driver mutations. LUAD-to-LU...
Alternative Titles
Full title
Comprehensive molecular characterization of lung tumors implicates AKT and MYC signaling in adenocarcinoma to squamous cell transdifferentiation
Authors, Artists and Contributors
Author / Creator
Taniguchi, Hirokazu
Zhan, Yingqian A.
Hasan, Maysun M.
Chavan, Shweta S.
Meng, Fanli
Uddin, Fathema
Allaj, Viola
Manoj, Parvathy
Shah, Nisargbhai S.
Chan, Joseph M.
Ciampricotti, Metamia
Chow, Andrew
Offin, Michael
Ray-Kirton, Jordana
Egger, Jacklynn D.
Bhanot, Umesh K.
Linkov, Irina
Asher, Marina
Roehrl, Michael H.
Ventura, Katia
Qiu, Juan
de Stanchina, Elisa
Chang, Jason C.
Rekhtman, Natasha
Houck-Loomis, Brian
Koche, Richard P.
Yu, Helena A.
Sen, Triparna
Rudin, Charles M.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_4c6ed1ab46b04936a848bae9af7bc67d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4c6ed1ab46b04936a848bae9af7bc67d
Other Identifiers
ISSN
1756-8722
E-ISSN
1756-8722
DOI
10.1186/s13045-021-01186-z
