Using viral diversity to identify HIV-1 variants under HLA-dependent selection in a systematic viral...
Using viral diversity to identify HIV-1 variants under HLA-dependent selection in a systematic viral genome-wide screen
About this item
Full title
Author / Creator
the Swiss HIV Cohort Study (SHCS) , Swiss HIV Cohort Study (SHCS) , Neuner-Jehle, Nadia , Zeeb, Marius , Thorball, Christian W. , Fellay, Jacques , Metzner, Karin J. , Frischknecht, Paul , Neumann, Kathrin , Leeman, Christine , Rauch, Andri , Stöckle, Marcel , Huber, Michael , Perreau, Matthieu , Bernasconi, Enos , Notter, Julia , Hoffmann, Matthias , Leuzinger, Karoline , Günthard, Huldrych F. , Pasin, Chloé and Kouyos, Roger D.
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
The pathogenesis of HIV-1 infection is governed by a highly dynamic, time-dependent interaction between the host and the viral genome. In this study, we developed a novel systematic approach to assess the host-virus interaction, using average pairwise viral diversity as a proxy for time since infection, and applied this method to nearly whole viral...
Alternative Titles
Full title
Using viral diversity to identify HIV-1 variants under HLA-dependent selection in a systematic viral genome-wide screen
Authors, Artists and Contributors
Author / Creator
Swiss HIV Cohort Study (SHCS)
Neuner-Jehle, Nadia
Zeeb, Marius
Thorball, Christian W.
Fellay, Jacques
Metzner, Karin J.
Frischknecht, Paul
Neumann, Kathrin
Leeman, Christine
Rauch, Andri
Stöckle, Marcel
Huber, Michael
Perreau, Matthieu
Bernasconi, Enos
Notter, Julia
Hoffmann, Matthias
Leuzinger, Karoline
Günthard, Huldrych F.
Pasin, Chloé
Kouyos, Roger D.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_4c8bd76294a344a5a8d9bd33b496838f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_4c8bd76294a344a5a8d9bd33b496838f
Other Identifiers
ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1012385
